If you spend time searching for your car keys or cell phone, you’re not alone. One survey found that in the past week, 39% of people forgot where they put everyday items. People 18 to 34 years old were more likely than seniors 55 and older to misplace car keys or not remember what day it was.1 Keeping your brain in tiptop shape is important no matter your age. That’s where Liposomal Citicoline from AlchePharma® Laboratories comes into play.
Want more information on Citicoline supplements for Vietnam? Feel free to contact us.
Citicoline increases attention, accuracy, focus, and memory.* It protects and repairs brain cells.* Citicoline’s cognitive benefits may be due to its structural similarity to phosphatidylcholine, the major component of each cell’s lipid membrane. Citicoline helps build acetylcholine, a brain chemical important for thinking and memory.* Enhance your brainpower by nourishing each cell with Liposomal Citicoline.*
Cognizin® citicoline, the form used in Liposomal Citicoline, ramped up brain energy by 14%.* In healthy adults, it sped up the formation of brain cell membranes by 26%, keeping the brain working at peak performance.* It also supports the brain’s blood vessels.*
When we age, phosphatidylcholine levels drop. This spells trouble for brain cells. Higher phosphatidylcholine levels are associated with better verbal learning, an important measure of cognition. In memory tests, older people who take citicoline are better able to recall words and objects.*
Liposomal Citicoline from AlchePharma® carries citicoline within a lipid bilayer. It’s absorbed quickly and easily, perfect for those with compromised gut function or who don’t like to swallow pills.
Cognizin®, branded citicoline, is a clinically studied2 nootropic that supports brain health and cognition, in an easy-to-use and great-tasting liquid.*
A little brain boost can go a far way, right? The truth of the matter is that a significant proportion of adults feel that their brain isn’t as efficient as it should be.
See, even if you aren’t in your advanced years, there is a lot to be gained by using well-timed supplements designed to enhance your memory and cognition. Also referred to as “Nootropics”,
these supplements can improve your focus or alertness to help you perform better at your job or even your workout.
Wondering what supplements can help to supercharge your brain? Let’s check them out now.
Ginkgo Biloba: 120-600mg
Huperzine A: 0.2-0.8mg
Bacopa Monnieri: 300-450mg
Citicoline: 250-2000mg
Ginkgo Biloba is an ancient Chinese herb used for centuries for its ability to boost important facets of brain health, such as focus and memory. It may also help mitigate the rate of age-related cognitive decline.
Ginkgo Biloba can be taken by people in general good health as a way to improve brain power. It can be a useful adjuvant for students that spend long nights studying or anyone seeking to improve mental acuity.
Total daily dosages of between 120-600mg daily is normal. Higher dosages than this will not lead to a superior experience but may increase the risk of side effects. It is also not advised to consume close to bedtime as it will interfere with restful sleep.
Ginkgo Biloba has a significant body of research behind it, which demonstrates its benefit for the brain.
For instance, the results of a 2011 trial published in the Journal of Phytomedicine found that over the course of 6 weeks, subjects aged between 45-56 were able to significantly improve their recollection ability (short term memory) when compared to placebo.
Smaller studies have also demonstrated its ability to improve cerebral blood flow, as was published in the Journal of Neuroradiology in 2011. Reduced blood viscosity and enhanced all over cerebral blood flow were reported in elderly men judged to be in good health.
In normal adult populations, side effects of ginkgo Biloba consumption are infrequent at recommended dose ranges. At higher dosages, insomnia, tremors, and increased heart rate is possible.
Interactions may also exist with anti-hypertensive medication, those used to treat heart failure or blood thinners. Be sure to consult your physician or pharmacist for guidance on these matters before starting consumption.
Huperzine A is a naturally occurring alkaloid found in the plant Huperzia Serrata native to the wet marshy areas of Asia. It acts by inhibiting the action of the enzyme acetylcholinesterase that breaks down acetylcholine- a key brain chemical involved in learning, memory, and focus.
Huperzine A can be highly beneficial for anyone suffering from cognitive impairment; such as people diagnosed with Alzheimer’s or Parkinson’s disease, to students looking to improve focus and retention, and even executives wanting to enhance their brain power and concentration on the job.
The recommended dosage of Huperzine A can be considered small, as daily consumption very scarcely exceeds 1mg. The most common dose range stands at between 0.2-0.8mg, taken preferably in split doses throughout the day.
Huperzine A has a half-life in the body of approximately 5 hours, so to maintain a stable blood level you will need to consume it at least twice daily (during awake hours).
Huperzine A is a thoroughly researched compound, and can arguably be considered the most promising supplement you can consume to improve your memory and cognition.
Effects On Memory
One double blind clinical trial published in the Chinese journal Zhongguo Yao Li Xue Bao compared the effects of Huperzine A against placebo in adolescent subjects.
Over the course of 4 weeks, Huperzine A administered at the dose of 100 micrograms twice daily yielded superior effects on memory and overall learning.
Effects On Accelerated Cognitive Decline
A reduction in cognitive abilities is expected with advancing age, but the onset of Alzheimer’s disease accelerated this process exponentially.
A study published in The International Journal of clinical and experimental pathology found that Huperzine A administration reduced inflammation and deposition of beta-amyloid protein in the brain, which both trigger neuronal cell death.
These findings are exciting because it means that the rate of cognitive decay can be mitigated with the use of Hup A.
There is also a strong likelihood that Huperzine A exerts a neuroprotective action on brain cells to protect against oxidative damage and environmental risk factors.
Side effects of Huperzine A supplementation are rare when taken at the recommended doses, but when they occur, tend to be cholinergic in nature.
This is owing to the neurotransmitter acetylcholine which is increased under the effects of Huperzine A.
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Side effects may include nausea, upset stomach, muscle weakness, and a reduced heart rate.
A plant native to Asia and Australia, this “weed” is likely the very first nootropic that was ever used. It is known as a stimulating and calming herb at the same time that can help support a range of cognitive benefits.
Bacopa Monnieri can be used by people across the age spectrum, ranging from students or executives that need a brain boost, to the older population seeking to offset cognitive decline. It may also be used to deal with acute or chronic stress and shows promise in managing ADHD.
The most commonly researched dosage of Bacopa Monnieri is in the range of 300-450mg daily. This refers to specific extract amounts, and not the overall amount of consumed plant powder.
Improves Cognition and Memory
Several studies have been conducted on Bacopa Monnieri when it comes to its potential for improving brain function.
A review of 9 studies involving a total of 518 subjects found that it positively improved cognition and attention selectivity, as well as reducing reaction times.
Yet another study found that it improved memory and can help counter the amnesic effect of date rape drugs.
Can Help Manage Depression and Stress States
Two small trials totaling 71 subjects found that Bacopa Monnieri could help reduce cortisol levels, known to have a negative impact on the memory centers of the brain. Other neurotransmitter changes such as lowered serotonin and dopamine levels experienced with an increased cortisol level are also countered via consumption of Bacopa.
When taken at researched levels, Bacopa Monnieri is very safe and only associated with mild adverse effects such as nausea. In rodent studies, high intake is associated with transient suppression of spermatogenesis (sperm production), which returns to normal quickly when the supplement is discontinued.
It may also potentiate the effect of tricyclic antidepressants such as amitriptyline so be sure to discuss any other medication/supplements you may be using with your health care provider.
Citicoline, otherwise known as CDP choline or cytidine-5-diphosphocholine is a molecule that raises levels of acetylcholine in the brain to boost memory, cognition, and also overall neuronal health.
Citicoline is safe for use for kids as well as adults. It can support learning even in states of malnutrition (according to animal studies), making it very useful in low-income settings.
It is also extremely promising in dealing with diseased brain states, including ischemia, dementia, or Alzheimer’s.
Citicoline's daily dosage ranges from 250-2000mg, although there may be some benefit from as little as 100mg.
Can Protect Against Cognitive Deficits As A Result Of Impoverishment
It’s not surprising that nutritional deficiency can affect brain function in kids and adults alike, but rodent studies done using Citicholine have found that this impact can be mitigated.
The findings, published in the Journal Learning Memory revealed that over the course of 3 months, showed that rats given CDP choline compensated for the malnourished states and displayed superior memory and retentive skills than the control group.
Improves Memory Deficits In Diseased States
Studies have found that administration of Citicholine can help arrest the speed of senile cognitive impairment, or that which occurs following brain injuries such as a stroke or physical trauma.
By helping to reinforce cellular membranes (consisting heavily of phosphatidylcholine) and reinforcing the synthesis of acetylcholine many of the adverse outcomes can be reduced.
Citicoline is found naturally in all cellular membranes found in humans. It is also naturally occurring in many foods we eat. However, because of its ability to increase levels of acetylcholine, cholinergic side effects such as nausea, diarrhea and increased perspiration are possible.
It may interact with anti-cholinergic medications, such as those used to help manage symptoms of Parkinson’s disease.
WHERE CAN I BUY A GOOD MEMORY SUPPLEMENT?
Made with effective, high-quality, ingredients, Dawn to Dusk was designed to be a better and healthier alternative to the old fashioned energy supplements. With as little caffeine as a single cup of coffee, Dawn to Dusk provides up to 10 hours of clean energy and helps improve mood, heighten mental focus, and boost productivity.
Unlike coffee and energy drinks where you feel an instant burst of energy and a crash later on, Dawn to Dusk give you a smoother and longer lasting supply of energy with no jitters, no afternoon crash, and of course, with no calories or sugar.
References:
Kaschel R. Specific memory effects of Ginkgo biloba extract EGb 761 in middle-aged healthy volunteers. Phytomedicine. 2011;18(14):1202-1207. doi:10.1016/j.phymed.2011.06.021
Mashayekh A, Pham DL, Yousem DM, Dizon M, Barker PB, Lin DD. Effects of Ginkgo biloba on cerebral blood flow assessed by quantitative MR perfusion imaging: a pilot study. Neuroradiology. 2011;53(3):185-191. doi:10.1007/s00234-010-0790-6
Sun QQ, Xu SS, Pan JL, Guo HM, Cao WQ. Huperzine-A capsules enhance memory and learning performance in 34 pairs of matched adolescent students. Zhongguo Yao Li Xue Bao. 1999;20(7):601-603.
Zhu N, Lin J, Wang K, Wei M, Chen Q, Wang Y. Huperzine A protects neural stem cells against Aβ-induced apoptosis in a neural stem cells and microglia co-culture system. Int J Clin Exp Pathol. 2015;8(6):6425-6433. Published 2015 Jun 1.
Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, Limpeanchob N, Norman Scholfield C. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol. 2014;151(1):528-535. doi:10.1016/j.jep.2013.11.008
Prabhakar, S., Saraf, M.K., Pandhi, P. et al. Bacopa monniera exerts antiamnesic effect on diazepam-induced anterograde amnesia in mice. Psychopharmacology 200, 27–37 (2008). https://doi.org/10.1007/s00213-007-1049-8
Sheikh N, Ahmad A, Siripurapu KB, Kuchibhotla VK, Singh S, Palit G. Effect of Bacopa monniera on stress induced changes in plasma corticosterone and brain monoamines in rats. J Ethnopharmacol. 2007;111(3):671-676. doi:10.1016/j.jep.2007.01.025
Fioravanti M, Buckley AE. Citicoline (Cognizin) in the treatment of cognitive impairment. Clin Interv Aging. 2006;1(3):247-251. doi:10.2147/ciia.2006.1.3.247
Teather LA, Wurtman RJ. Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats. Learn Mem. 2005;12(1):39-43. doi:10.1101/lm.83905
de la Morena E. Efficacy of CDP-choline in the treatment of senile alterations in memory. Ann N Y Acad Sci. 1991;640:233-236. doi:10.1111/j.1749-6632.1991.tb00224.x
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